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pubmed-article:10543930pubmed:abstractTextThe mechanism of persistent neurohormonal and cardiorespiratory reflex abnormalities in chronic heart failure remain unclear. Also, why chronic heart failure patients who develop cachexia demonstrate a particularly abnormal neurohormonal profile and have a high risk of death is not known. Impaired reflex control within the cardiac and respiratory systems, and abnormal heart rate variability have both been linked to a poor outcome. Muscle reflexes may contribute to persistent neurohormonal overactivity in wasted patients. Thus, we hypothesized that patients with cardiac cachexia might exhibit particularly profound abnormalities in cardiorespiratory reflexes and heart ratevariability. METHODS andlld:pubmed
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pubmed-article:10543930pubmed:copyrightInfoCopyright 1999 The European Society of Cardiology.lld:pubmed
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pubmed-article:10543930pubmed:articleTitleThe impact of cachexia on cardiorespiratory reflex control in chronic heart failure.lld:pubmed
pubmed-article:10543930pubmed:affiliationDepartment of Cardiac Medicine, Imperial College, National Heart & Lung Institute and Royal Brompton Hospital, London, U.K.lld:pubmed
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