|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
1999-9-9
|
|
pubmed:databankReference |
|
|
pubmed:abstractText |
Systemic acquired resistance (SAR) is a plant immune response induced after a local infection by necrotizing pathogens. The Arabidopsis NPR1 gene is a positive regulator of SAR, essential for transducing the SAR signal salicylic acid (SA). Mutations in the NPR1 gene abolish the SA-induced expression of pathogenesis-related (PR) genes and resistance to pathogens. To identify additional regulators of SAR, we screened for suppressors of npr1-1. In the npr1-1 background, the sni1 (suppressor of npr1-1, inducible 1) mutant shows near wild-type levels of PR1 expression and resistance to pathogens after induction. Restoration of SAR in npr1-1 by the recessive sni1 mutation indicates that wild-type SNI1 may function as a negative regulator of SAR. We cloned the SNI1 gene and found that it encodes a leucine-rich nuclear protein.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
0092-8674
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
6
|
|
pubmed:volume |
98
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
329-39
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:10458608-Amino Acid Sequence,
pubmed-meshheading:10458608-Animals,
pubmed-meshheading:10458608-Arabidopsis,
pubmed-meshheading:10458608-Arabidopsis Proteins,
pubmed-meshheading:10458608-Base Sequence,
pubmed-meshheading:10458608-Chromosome Mapping,
pubmed-meshheading:10458608-Cloning, Molecular,
pubmed-meshheading:10458608-DNA, Complementary,
pubmed-meshheading:10458608-Gene Expression Regulation, Plant,
pubmed-meshheading:10458608-Genes, Plant,
pubmed-meshheading:10458608-Genes, Suppressor,
pubmed-meshheading:10458608-Glucuronidase,
pubmed-meshheading:10458608-Mice,
pubmed-meshheading:10458608-Molecular Sequence Data,
pubmed-meshheading:10458608-Mutagenesis, Site-Directed,
pubmed-meshheading:10458608-Nuclear Proteins,
pubmed-meshheading:10458608-Plant Proteins,
pubmed-meshheading:10458608-Plants, Genetically Modified,
pubmed-meshheading:10458608-Pseudomonas,
pubmed-meshheading:10458608-Recombinant Fusion Proteins,
pubmed-meshheading:10458608-Retinoblastoma Protein,
pubmed-meshheading:10458608-Sequence Alignment,
pubmed-meshheading:10458608-Sequence Homology, Amino Acid,
pubmed-meshheading:10458608-Signal Transduction
|
|
pubmed:year |
1999
|
|
pubmed:articleTitle |
Identification and cloning of a negative regulator of systemic acquired resistance, SNI1, through a screen for suppressors of npr1-1.
|
|
pubmed:affiliation |
Developmental, Cell, and Molecular Biology Group, Department of Botany, Duke University, Durham, North Carolina 27708-1000, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
|
