Linked Life Data

10456327

Source:http://linkedlifedata.com/resource/pubmed/id/10456327

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1999-8-30
pubmed:databankReference
pubmed:abstractText
Autocrine motility factor receptor (AMFR) is a cell surface glycoprotein of molecular weight 78,000 (gp78), mediating cell motility signaling in vitro and metastasis in vivo. Here, we cloned the full-length cDNAs for both human and mouse AMFR genes. Both genes encode a protein of 643 amino acids containing a seven transmembrane domain, a RING-H2 motif and a leucine zipper motif and showed a 94.7% amino acid sequence identity to each other. Analysis of the amino acid sequence of AMFR with protein databases revealed no significant homology with all known seven transmembrane proteins, but a significant structural similarity to a hypothetical protein of Caenorhabditis elegans, F26E4.11. Thus, AMFR is a highly conserved gene which encodes a novel type of seven transmembrane protein.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0014-5793
pubmed:author
pubmed:issnType
Print
pubmed:day
6
pubmed:volume
456
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
295-300
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed-meshheading:10456327-Amino Acid Sequence, pubmed-meshheading:10456327-Animals, pubmed-meshheading:10456327-Base Sequence, pubmed-meshheading:10456327-Caenorhabditis elegans, pubmed-meshheading:10456327-Chromosome Mapping, pubmed-meshheading:10456327-Cloning, Molecular, pubmed-meshheading:10456327-DNA, Complementary, pubmed-meshheading:10456327-DNA Primers, pubmed-meshheading:10456327-Gene Expression, pubmed-meshheading:10456327-Humans, pubmed-meshheading:10456327-Mice, pubmed-meshheading:10456327-Molecular Sequence Data, pubmed-meshheading:10456327-Molecular Weight, pubmed-meshheading:10456327-Receptors, Autocrine Motility Factor, pubmed-meshheading:10456327-Receptors, Cytokine, pubmed-meshheading:10456327-Sequence Homology, Amino Acid, pubmed-meshheading:10456327-Ubiquitin-Protein Ligases
pubmed:year
1999
pubmed:articleTitle
The autocrine motility factor receptor gene encodes a novel type of seven transmembrane protein.
pubmed:affiliation
Biology Division, National Cancer Center Research Institute, Tokyo, Japan.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't