Source:http://linkedlifedata.com/resource/pubmed/id/10379017
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
25
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pubmed:dateCreated |
1999-6-24
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pubmed:abstractText |
Although their clinical efficacy is unclear and they may cause serious adverse effects, systemic glucocorticoids are a standard treatment for patients hospitalized with exacerbations of chronic obstructive pulmonary disease (COPD). We conducted a double-blind, randomized trial of systemic glucocorticoids (given for two or eight weeks) or placebo in addition to other therapies, for exacerbations of COPD. Most other care was standardized over the six-month period of follow-up. The primary end point was treatment failure, defined as death from any cause or the need for intubation and mechanical ventilation, readmission to the hospital for COPD, or intensification of drug therapy.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0028-4793
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
24
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pubmed:volume |
340
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1941-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10379017-Administration, Oral,
pubmed-meshheading:10379017-Aged,
pubmed-meshheading:10379017-Double-Blind Method,
pubmed-meshheading:10379017-Drug Administration Schedule,
pubmed-meshheading:10379017-Drug Therapy, Combination,
pubmed-meshheading:10379017-Forced Expiratory Volume,
pubmed-meshheading:10379017-Glucocorticoids,
pubmed-meshheading:10379017-Hospitalization,
pubmed-meshheading:10379017-Humans,
pubmed-meshheading:10379017-Hyperglycemia,
pubmed-meshheading:10379017-Infusions, Intravenous,
pubmed-meshheading:10379017-Length of Stay,
pubmed-meshheading:10379017-Lung Diseases, Obstructive,
pubmed-meshheading:10379017-Male,
pubmed-meshheading:10379017-Methylprednisolone,
pubmed-meshheading:10379017-Prednisone,
pubmed-meshheading:10379017-Treatment Failure
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pubmed:year |
1999
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pubmed:articleTitle |
Effect of systemic glucocorticoids on exacerbations of chronic obstructive pulmonary disease. Department of Veterans Affairs Cooperative Study Group.
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pubmed:affiliation |
Veterans Affairs Medical Center in Minneapolis, MN 55417, USA. niewo001@maroon.tc.umn.edu
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, Non-P.H.S.,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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