Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1999-6-29
pubmed:abstractText
The characteristics of single K+ channels in cultured cerebellar granule neurons of neonatal rat were studied by the cell- attached and inside-out configurations of patch clamp technique. The results are as follows: the predominant conductance of single channel was 25PS, the currents amplitude, the mean open time and the open probability were dependent of membrane potential, the open time distribution histograms were fitted by two exponential components, the channel activity was not inactivated during 20 s period, independent of calcium and blocked by tetraethylammonium. These results indicated that the single channel was a delayed rectifier (Ik). It is suggested that the non-inactivating channel with conductance of 25pS which exists in the cerebellar granule cell might be a new subtype of Ik channel.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1000-6834
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
329-32
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
[Physiological characteristics of single K+ channel currents (Ik) in cerebellar cortical neurons of neonatal rat].
pubmed:affiliation
Department of Physiology, Sun Yat-Sen University of Medical Sciences, Guangzhou.
pubmed:publicationType
Journal Article, English Abstract