Linked Life Data

10147444

Source:http://linkedlifedata.com/resource/pubmed/id/10147444

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1994-11-23
pubmed:abstractText
Tissue specimens retrieved from four regions adjacent to hip implants during revision surgery were subjected to a novel treatment to make possible the quantitative separation of residual metal particulates and metal reaction products (metal ions and metal-protein complexes). The tissues were exposed to sodium hypochlorite solution that degraded and solubilized them, liberating metal reaction product and leaving behind metal wear particles, which were separated by centrifugation. Atomic absorption spectrophotometry was used to analyze the concentrations of the separated metal ions and wear particles. Co ion concentrations were 0.05 to 0.9 mM, Cr ion concentrations were 0.04 to 2.1 mM, and of Ti ion concentrations were 0.30 to 0.60 mM. The weight of Co metal particles was 0.1 to 4.9 mg/100 mg tissue, of Cr metal particles 0.07 to 2.2 mg/100 mg of tissue, and Ti particles 0.09 to 5.2 mg/100 mg tissue; one black tissue sample contained 3333 mg Ti/100 mg tissue. No correlation was found between the concentrations of these two entities in the samples examined, probably due to the complex and varied processes creating them. The procedures discussed here will result in data that can help elucidate the separate contributions of metal reaction products and metal particulates to implant loosening.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
T
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1045-4861
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
191-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
A new technique for quantitation of metal particulates and metal reaction products in tissues near implants.
pubmed:affiliation
Departments of Bioengineering and Orthopaedic Surgery, Hospital for Joint Diseases Orthopaedic Institute, New York 10003.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't