Linked Life Data

1012976

Source:http://linkedlifedata.com/resource/pubmed/id/1012976

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1977-3-21
pubmed:abstractText
In rats central chemical sympathectomy (CCS) was elicited by intracerebro-ventricular (icv) injection of two doses of 250 mug of 6-hydroxydopamine (6-OHDA) at 48 hr interval. 7 days after the last injection when full CCS is developed, 10 mug of dopamine (DA) or 5-hydroxytryptamine (5-HT) were applied icv and locomotor and exploratory activity and irritability of animals were measured. CCS reversed the depressive effect of DA on the locomotor and exploratory activity, and intensified irribability of animals. It intensified the effect of 5-HT on the exploratory activity without changing the others observed behavioral parameters. It is concluded that CCS changes reactivity of central nervous system of pharmacological effects of DA and slightly affects the central response to 5-HT.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0301-0244
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
463-7
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Behavioural effects of dopamine and 5-hydroxytryptamine in centrally chemosympathectomized rats.
pubmed:publicationType
Journal Article