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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1999-4-19
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pubmed:abstractText |
The performance of antibody detection, antigen detection, and Aspergillus genus-specific PCR for diagnosing Aspergillus meningitis was investigated with 26 cerebrospinal fluid (CSF) samples obtained from a single patient with proven infection caused by Aspergillus fumigatus. Immunoglobulin G antibodies directed against Aspergillus were not detected by enzyme-linked immunosorbent assay in CSF or serum. The antigen galactomannan was detected in the CSF 45 days before a culture became positive, and Aspergillus DNA was detected 4 days prior to culture. Decline of the galactomannan antigen titer in the CSF during treatment with intravenous and intraventricular amphotericin B and intravenous voriconazole corresponded with the clinical response to treatment.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-1321697,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-1327616,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-1407438,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-1600262,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-1655460,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-2267490,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-2277197,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-2995303,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-3512781,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-6349340,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-6401419,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-6657000,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-6893266,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-7103428,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-7200204,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-7596522,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-7714217,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-7726488,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-7769291,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-7929762,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-8532052,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-8642177,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-8749640,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-8953083,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-9108182,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-9207418,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10074549-946540
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Amphotericin B,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Fungal,
http://linkedlifedata.com/resource/pubmed/chemical/Antifungal Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Fungal,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Fungal,
http://linkedlifedata.com/resource/pubmed/chemical/Mannans,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrimidines,
http://linkedlifedata.com/resource/pubmed/chemical/Triazoles,
http://linkedlifedata.com/resource/pubmed/chemical/galactomannan,
http://linkedlifedata.com/resource/pubmed/chemical/voriconazole
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0095-1137
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1186-9
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:10074549-Aged,
pubmed-meshheading:10074549-Amphotericin B,
pubmed-meshheading:10074549-Antibodies, Fungal,
pubmed-meshheading:10074549-Antifungal Agents,
pubmed-meshheading:10074549-Antigens, Fungal,
pubmed-meshheading:10074549-Aspergillosis,
pubmed-meshheading:10074549-Aspergillus fumigatus,
pubmed-meshheading:10074549-DNA, Fungal,
pubmed-meshheading:10074549-Drug Resistance, Microbial,
pubmed-meshheading:10074549-Female,
pubmed-meshheading:10074549-Humans,
pubmed-meshheading:10074549-Mannans,
pubmed-meshheading:10074549-Meningitis, Fungal,
pubmed-meshheading:10074549-Mycology,
pubmed-meshheading:10074549-Polymerase Chain Reaction,
pubmed-meshheading:10074549-Pyrimidines,
pubmed-meshheading:10074549-Time Factors,
pubmed-meshheading:10074549-Triazoles
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pubmed:year |
1999
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pubmed:articleTitle |
Aspergillus meningitis: diagnosis by non-culture-based microbiological methods and management.
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pubmed:affiliation |
Departments of Medical Microbiology, University Hospital Nijmegen, Nijmegen, The Netherlands. p.verweij@mmb.azn.nl
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pubmed:publicationType |
Journal Article,
Case Reports
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