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pubmed-article:10037800pubmed:abstractTextSox proteins belong to the HMG box superfamily of DNA-binding proteins and are found throughout the animal kingdom. They are involved in the regulation of such diverse developmental processes as germ layer formation, organ development and cell type specifi-cation. Hence, deletion or mutation of Sox proteins often results in developmental defects and congenital disease in humans. Sox proteins perform their function in a complex interplay with other transcription factors in a manner highly dependent on cell type and promoter context. They exhibit a remarkable crosstalk and functional redundancy among each other.lld:pubmed
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pubmed-article:10037800pubmed:articleTitleFrom head to toes: the multiple facets of Sox proteins.lld:pubmed
pubmed-article:10037800pubmed:affiliationZentrum für Molekulare Neurobiologie, Universität Hamburg, Martinistrasse 52, D-20246 Hamburg, Germany. wegner@uke.uni-hamburg.delld:pubmed
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