| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... |
cpath:CPATH-LOCAL-268120,
cpath:CPATH-LOCAL-268120,
cpath:CPATH-LOCAL-268121,
cpath:CPATH-LOCAL-268121,
cpath:CPATH-LOCAL-268122,
cpath:CPATH-LOCAL-268122,
cpath:CPATH-LOCAL-268123,
cpath:CPATH-LOCAL-268123,
cpath:CPATH-LOCAL-268124,
cpath:CPATH-LOCAL-268124,
cpath:CPATH-LOCAL-270800,
cpath:CPATH-LOCAL-270800
|
| http://www.biopax.org/relea... |
Ski oncogene,
Ski oncogene
|
| http://www.biopax.org/relea... |
SKI_HUMAN,
SKI_HUMAN
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Proto-oncogene c-Ski,
Proto-oncogene c-Ski
|
| http://www.biopax.org/relea... |
FUNCTION: May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Functions as a repressor of TGF-beta signaling. SUBUNIT: Interacts with SMAD2, SMAD3 and SMAD4. Interacts with HIPK2. Part of a complex with HIPK2 and SMAD1/2/3. Interacts with PRDM16 and SMAD3; the interaction with PRDM16 promotes the recruitment SMAD3-HDAC1 complex on the promoter of TGF-beta target genes. SUBCELLULAR LOCATION: Nucleus. SIMILARITY: Belongs to the SKI family. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
FUNCTION: May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Functions as a repressor of TGF-beta signaling. SUBUNIT: Interacts with SMAD2, SMAD3 and SMAD4. Interacts with HIPK2. Part of a complex with HIPK2 and SMAD1/2/3. Interacts with PRDM16 and SMAD3; the interaction with PRDM16 promotes the recruitment SMAD3-HDAC1 complex on the promoter of TGF-beta target genes. SUBCELLULAR LOCATION: Nucleus. SIMILARITY: Belongs to the SKI family. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
|
| skos:exactMatch | |
| skos:closeMatch |