| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
Cadherin-2
|
| http://www.biopax.org/relea... |
CADH2_MOUSE
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
CD325,
N-cadherin,
Neural cadherin
|
| http://www.biopax.org/relea... |
FUNCTION: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density. SUBUNIT: Interacts with CDCP1 (By similarity). Interacts with PCDH8; this complex may also include TAOK2 (By similarity). The interaction with PCDH8 may lead to internalization through TAOK2/p38 MAPK pathway. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. DEVELOPMENTAL STAGE: Expressed at all stages of testicular development with highest levels found in testes of 21-day-old mice. SIMILARITY: Contains 5 cadherin domains. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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| skos:exactMatch | |
| skos:closeMatch |