Linked Life Data

CPATH-32883

Source:http://cbio.mskcc.org/cpath#CPATH-32883

Statements in which the resource exists.
SubjectPredicateObjectContext
cpath:CPATH-32883rdf:typehttp://www.biopax.org/relea...lld:biogrid
cpath:CPATH-32883http://www.biopax.org/relea...cpath:CPATH-LOCAL-134452lld:biogrid
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cpath:CPATH-32883http://www.biopax.org/relea...cpath:CPATH-LOCAL-139284lld:biogrid
cpath:CPATH-32883http://www.biopax.org/relea...Macrophage colony-stimulating factor 1lld:biogrid
cpath:CPATH-32883http://www.biopax.org/relea...CSF1_HUMANlld:biogrid
cpath:CPATH-32883http://www.biopax.org/relea...cpath:CPATH-LOCAL-134466lld:biogrid
cpath:CPATH-32883http://www.biopax.org/relea...Lanimostimlld:biogrid
cpath:CPATH-32883http://www.biopax.org/relea...MCSFlld:biogrid
cpath:CPATH-32883http://www.biopax.org/relea...CSF-1lld:biogrid
cpath:CPATH-32883http://www.biopax.org/relea...Processed macrophage colony-stimulating factor 1lld:biogrid
cpath:CPATH-32883http://www.biopax.org/relea...M-CSFlld:biogrid
cpath:CPATH-32883http://www.biopax.org/relea...FUNCTION: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF- 1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. SUBUNIT: Homodimer or heterodimer; disulfide-linked. SUBCELLULAR LOCATION: Cell membrane; Single-pass membrane protein (By similarity). SUBCELLULAR LOCATION: Processed macrophage colony-stimulating factor 1: Secreted, extracellular space (By similarity). ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=P09603-1; Sequence=Displayed; Name=2; IsoId=P09603-2; Sequence=VSP_001188; Name=3; IsoId=P09603-3; Sequence=VSP_001187; PTM: Glycosylation and proteolytic cleavage yield different soluble forms. A high molecular weight soluble form is a proteoglycan containing chondroitin sulfate. PTM: Isoform 1 is N- and O-glycosylated. Isoform 3 is N- glycosylated. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.lld:biogrid
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cpath:CPATH-LOCAL-11520654http://www.biopax.org/relea...cpath:CPATH-32883lld:biogrid
cpath:CPATH-LOCAL-11673490http://www.biopax.org/relea...cpath:CPATH-32883lld:biogrid