| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... |
cpath:CPATH-LOCAL-134452,
cpath:CPATH-LOCAL-134453,
cpath:CPATH-LOCAL-134454,
cpath:CPATH-LOCAL-134455,
cpath:CPATH-LOCAL-134456,
cpath:CPATH-LOCAL-134457,
cpath:CPATH-LOCAL-134458,
cpath:CPATH-LOCAL-134459,
cpath:CPATH-LOCAL-134460,
cpath:CPATH-LOCAL-134461,
cpath:CPATH-LOCAL-134462,
cpath:CPATH-LOCAL-134463,
cpath:CPATH-LOCAL-134464,
cpath:CPATH-LOCAL-134465,
cpath:CPATH-LOCAL-139284
|
| http://www.biopax.org/relea... |
Macrophage colony-stimulating factor 1
|
| http://www.biopax.org/relea... |
CSF1_HUMAN
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
CSF-1,
Lanimostim,
M-CSF,
MCSF,
Processed macrophage colony-stimulating factor 1
|
| http://www.biopax.org/relea... |
FUNCTION: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF- 1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. SUBUNIT: Homodimer or heterodimer; disulfide-linked. SUBCELLULAR LOCATION: Cell membrane; Single-pass membrane protein (By similarity). SUBCELLULAR LOCATION: Processed macrophage colony-stimulating factor 1: Secreted, extracellular space (By similarity). ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=P09603-1; Sequence=Displayed; Name=2; IsoId=P09603-2; Sequence=VSP_001188; Name=3; IsoId=P09603-3; Sequence=VSP_001187; PTM: Glycosylation and proteolytic cleavage yield different soluble forms. A high molecular weight soluble form is a proteoglycan containing chondroitin sulfate. PTM: Isoform 1 is N- and O-glycosylated. Isoform 3 is N- glycosylated. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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| skos:exactMatch | |
| skos:closeMatch |