| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
NAD-dependent deacetylase hst4
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| http://www.biopax.org/relea... |
HST4_SCHPO
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
3.5.1.-,
Homologous to SIR2 protein 4
|
| http://www.biopax.org/relea... |
FUNCTION: NAD-dependent histone deacetylase, which contributes to both telomeric and centromeric silencing, proper cell cycle progression, DNA damage control, recombination, and genomic maintenance. CATALYTIC ACTIVITY: NAD(+) + an acetylprotein = nicotinamide + O- acetyl-ADP-ribose + a protein. COFACTOR: Binds 1 zinc ion per subunit (By similarity). SUBCELLULAR LOCATION: Nucleus, nucleolus. SIMILARITY: Belongs to the sirtuin family. SIMILARITY: Contains 1 deacetylase sirtuin-type domain. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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