Source:http://linkedlifedata.com/resource/chebi/id/CHEBI:66910
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"An indazole substituted at position 3 by a 2-(pyridin-2-yl)vinyl group and at position 6 by a 2-(N-methylaminocarboxy)phenylsulfanyl group. Used for the treatment of advanced renal cell carcinoma after failure of a first line systemic treatment." []
|
| skos:inScheme | |
| skos:prefLabel |
axitinib
|
| skos:altLabel |
N-methyl-2-({3-[(E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzamide
|
| skos:notation |
ChemIDplus:319460-85-0 "CAS Registry Number",
CiteXplore:20740300 "PubMed citation",
CiteXplore:21301929 "PubMed citation",
CiteXplore:21670972 "PubMed citation",
CiteXplore:22168366 "PubMed citation",
CiteXplore:22170007 "PubMed citation",
CiteXplore:22248343 "PubMed citation",
CiteXplore:22504156 "PubMed citation",
CiteXplore:22545314 "PubMed citation",
CiteXplore:22549112 "PubMed citation",
CiteXplore:22644797 "PubMed citation",
CiteXplore:22683928 "PubMed citation",
CiteXplore:22699078 "PubMed citation",
CiteXplore:22706540 "PubMed citation",
CiteXplore:22733795 "PubMed citation",
CiteXplore:22787405 "PubMed citation",
KEGG DRUG:319460-85-0 "CAS Registry Number",
KEGG DRUG:D03218 "KEGG DRUG",
Reaxys:11333336 "Reaxys Registry Number",
Wikipedia:Axitinib "Wikipedia"
|
| skos:broader | |
| skos:relatedSynonym |
axitinib,
N-methyl-2-({3-[(E)-2-(pyridin-2-yl)vinyl]-1H-indazol-6-yl}sulfanyl)benzamide,
AG-013736,
Inlyta,
axitinibum,
C22H18N4OS,
CNC(=O)c1ccccc1Sc1ccc2c(\\C=C\\c3ccccn3)n[nH]c2c1,
InChI=1S/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+,
InChIKey=RITAVMQDGBJQJZ-FMIVXFBMSA-N
|